| No. |
NBCT No. |
姓名 |
服務單位 |
題目 |
病例數 |
檢體類別 |
通過日期 |
| 1 |
200026 |
黃昭誠 |
高雄長庚醫院；解剖病理科 |
分析Delta-like 1 Homolog （DLK1）在肝癌T細胞免疫監控所扮演的角色 Investigating the Role of Delta-like 1 Homolog （DLK1） in T Cell Immune Surveillance of Hepatocellular Carcinoma |
80 |
Unstained tissue sections
|
20200522 |
| 2 |
200028 |
鄭國祥 |
亞東醫院；一般外科 |
探討抑制刺蝟訊息途徑以增加肝細胞癌對於doxorubicin之敏感度的 角色–體外及體內之研究 To investigate the role of inhibition of sonic Hedgehog signaling pathway in increasing the sensitivity of doxorubicin in hepatocellular carcinoma-an in vitro and in vivo study |
20 |
1.Tissue RNA
2.Unstained tissue sections
|
20200525 |
| 3 |
200029 |
林明宗 |
高雄長庚醫院；胃腸肝膽科系 |
肝細胞癌與肝纖維化病患血清中生物標記分析 Biomarkers analysis for hepatocellular carcinoma and liver fibrosis |
20 |
Serum
|
20200525 |
| 4 |
200032 |
郭光泰 |
雙和醫院；胸腔外科 |
將BTK-ITK途徑作為標靶以克服肺癌治療的抗藥性以及抑制腦轉移的策略 Targeting the BTK-ITK axis as a potential therapeutic strategy for overcoming drug resistance and inhibiting brain metastasis in lung cancer |
48 |
Unstained tissue sections
|
20200525 |
| 5 |
200001 |
楊順發 |
中山醫學大學附設醫院；臨床研究中心 |
LncRNA基因變異與肝癌的臨床表徵之研究 Study of the LncRNA genetic variants in hepatocellular carcinoma |
400 |
Blood DNA
|
20200526 |
| 6 |
200023 |
何明志 |
台大醫院；外科部 |
以具特異性的人類和B型肝炎病毒嵌合體DNA作為肝移植後肝癌復發的預測標記（2） Specific HBV-human chimera DNA as a novel biomarker for predicting the outcome of HCC after transplantation （2） |
136 |
1.Serum
2.Plasma
3.Tissue DNA
|
20200612 |
| 7 |
200031 |
蔡坤志 |
臺北醫學大學；臨床醫學研究所 |
ASPM與 Wnt訊息傳導在肝癌幹原性與惡化以及相關奈米基因治療之開發 The role of ASPM-Wnt signaling in hepatoma cancer stemness and progression and the development of the related nano- and gene-therapy |
100 |
Unstained tissue sections
|
20200612 |
| 8 |
200045 |
高明蔚 |
義大醫療財團法人義大醫院；胸腔外科 |
肺腺癌中血管擬態的基因表現 Gene expressions of vasculogenic mimicry in lung adenocarcinoma |
50 |
1.Unstained tissue sections
2.Tissue RNA
|
20200612 |
| 9 |
200021 |
陳建勳 |
中國醫藥大學附設醫院；胸腔外科部 |
探討肺癌多體（或組）學標記的臨床意義 Exploring the clinical significance of multi-omic markers of lung cancer |
75 |
1.Unstained tissue sections
2.Tissue RNA
|
20200702 |
| 10 |
200048 |
陳耀森 |
義大醫院；一般外科 |
探討胺基酸訊息傳遞路徑之第-GATOR複合體/mTOR複合體在肝癌形成之研究 To study amino-acid-dependent GATORC1/mTORC1 signaling in the development of hepatocellular carcinoma |
90 |
1.Unstained tissue sections
2.Unstained tissue array sections
3.Serum
|
20200702 |
| 11 |
200053 |
翁菁甫 |
新竹國泰綜合醫院；呼吸胸腔科 |
CAR蛋白在肺癌細胞之角色與流感病毒感染造成肺腫瘤形 成機制之探討 The role of CAR expression in human lung cancer and analysis the mechanism of respiratory associated virus infection in lung epithelial cell tumorigenesis |
100 |
Unstained tissue sections
|
20200717 |
| 12 |
200025 |
謝青華 |
高雄長庚醫院；整形外科 |
利用血液之生物標誌來篩檢出肝癌病患-根據台灣國家級人體生物資 料庫整合平台樣本之研究 Using circulating biomarkers to identify the patients with hepatocellular carcinoma-based on the samples from National Biobank Consortium of Taiwan |
50 |
1.Serum
2.Buffy coat
3.Unstained tissue sections
|
20200722 |
| 13 |
200049 |
黃志揚 |
佛教慈濟醫療財團法人 花蓮慈濟醫院；心血管暨粒腺體相關疾病研究中心 |
探討大腸直腸癌、肺癌與肝癌之基因與分子機轉研究 Study the genes and molecular mechanisms affecting of colorectal cancer, lung cancer and liver cancer |
39 |
1.Tissue RNA
2.Unstained tissue sections
3.Unstained tissue array sections
|
20200814 |
| 14 |
200058 |
許瀚水 |
臺北榮民總醫院；胸腔外科 |
Collagen XVII在肺癌幹細胞中多功能基因表現與代謝重整之角色及 相關機轉探討 The Role of Collagen XVII in the Pluripotent Gene Expression and Metabolic Reprogramming of Lung Cancer Stem Cells |
100 |
Unstained tissue sections
|
20200814 |
| 15 |
200024 |
張育平 |
高雄長庚醫院；胸腔內科 |
表皮生長因子接受器基因突變之肺腺癌合併腦轉移的病人其免疫生物標記與病理表現之關聯性 Immune biomarkers and pathology correlation in lung adenocarcinoma patients with epidermal growth factor receptor gene mutation and brain metastasis |
60 |
Unstained tissue sections
|
20200821 |
| 16 |
200035 |
馮博皓 |
雙和醫院；胸腔內科 |
探討CD155/TIGIT在類骨髓衍生抑制細胞/腫瘤衍生巨噬細胞誘導自然殺手細胞失調的機轉- 研究肺癌病人免疫檢查點阻斷藥物抗藥性機轉 The role and mechanism of CD155/TIGIT in MDSC/TAM induced NK cell dysfunction -A link to lung cancer resistance to immune checkpoint blockade |
60 |
1.Serum
2.Tissue DNA
3.Tissue RNA
4.Unstained tissue sections
|
20200825 |
| 17 |
200038 |
黃棣棟 |
臺北醫學大學附設醫院；神經外科 |
整合台灣兒童癌症臨床治療及分子診斷 Integration of treatment strategies and molecular diagnosis for childhood cancers in Taiwan |
5 |
Unstained tissue sections
|
20200909 |
| 18 |
200054 |
楊文祺 |
義大醫院；血液腫瘤科 |
局部及侵犯性肝細胞癌之免疫標記 Immune landmark in local limited HCC and advanced HCC |
210 |
1.Tissue RNA
2.Unstained tissue sections
|
20200924 |
| 19 |
200004 |
郭昶甫 |
長庚醫療財團法人長庚醫院；風濕過敏免疫科 |
利用可視化檢測轉座酶易接近的染色質（ATAC-see/seq）技術建立預測RA 患者使用最佳生物製劑之模式 Using ATAC-see/seq to establish the pre-screen model to determine the best biological agents for rheumatoid arthritis patients |
60 |
1.Blood DNA
2.Plasma
3.Buffy coat
|
20201110 |
| 20 |
200030 |
邱彥霖 |
醫療財團法人徐元智先生醫藥基金會亞東紀念醫院；腎臟內科 |
慢性腎病引發加速動脈硬化疾病之機制：探討巨細胞病毒 感染及免疫老化現 象為中介因子 Novel mechanism of accelerated atherosclerosis in renal failure: roles of immunosenescence and cytomegalovirus infection |
30 |
1.Plasma
2.Buffy coat
|
20201110 |
| 21 |
200050 |
胡智棻 |
三軍總醫院；小兒科部 |
腳趾骨腕骨併聯症候群的家族基因研究及基因功能分析 The novel gene/variant study of tarsal-carpal coalition syndrome from a family |
4 |
Blood DNA
|
20201110 |
| 22 |
200051 |
蒙恩 |
三軍總醫院；泌尿外科 |
以患者尿液菌相基因分析其骨盆腔疼痛症候群之影響機制 Investigating the mechanism of chronic pelvic pain syndrome by patients’ microbiota composition in urine |
30 |
Blood DNA
|
20201110 |
| 23 |
200052 |
宋志建 |
三軍總醫院；腎臟內科 |
腎臟疾病之尿液外泌體中miRNA鑑定與分析 Identification and Analysis of Urinary Exosomal miRNA in Patients with Kidney Disease |
10 |
Serum
|
20201110 |
| 24 |
200059 |
施宇隆 |
三軍總醫院；內科部胃腸科 |
NKX6.1基因高度甲基化與大腸直腸癌抗藥性之關聯性研究 -用藥指 引生物指標與其生理意義 Study on the association between NKX6.1 hypermethylation and chemoresistance in colorectal cancer - biomarker for therapy selection and its physiological role |
30 |
Plasma
|
20201110 |
| 25 |
200061 |
孫樵隱 |
基隆長庚醫院；腎臟科 |
必需性微量元素和慢性腎臟疾病：心血管和腎臟疾病預後之關聯性研究 Essential trace elements and chronic kidney disease: association with cardiovascular and kidney outcomes |
50 |
Serum
|
20201110 |
| 26 |
200063 |
胡瑜峰 |
臺北榮民總醫院；心臟內科 |
右心室出口處心律不整的泛基因體掃描遺傳相關研究 Genomewide Association Study of Right Ventricular Outflow Tract Ventricular Arrhythmia |
100 |
Blood DNA
|
20201110 |
| 27 |
200060 |
黃以信 |
臺北榮民總醫院；內科部胃腸肝膽科 |
磺胺劑引起肝傷害之藥物基因學研究 Pharmacogenetic study of sulfonamide-induced liver injury |
200 |
Blood DNA
|
20201111 |
| 28 |
200014 |
李文珍 |
臺中榮民總醫院；醫學研究部 |
探討台灣冠心症患者的家族性高膽固醇血症基因型 Familial Hypercholesterolemia Genotype in Taiwanese Patients with Coronary Heart Disease |
300 |
Buffy coat
|
20201112 |
| 29 |
200037 |
林裕誠 |
亞東紀念醫院；小兒部 |
IRGM調控之細胞自噬作用與腸道細菌叢間的交互作用對於非酒精性脂肪肝疾病的影響 The Interaction of IRGM-Mediated Autophagy and Gut Microbiota in Nonalcoholic Fatty Liver Disease |
100 |
Blood DNA
|
20201112 |
| 30 |
200036 |
林曜祥 |
高雄榮民總醫院；耳鼻喉科 |
腫瘤纖維母細胞分子改變對頭頸癌抗藥性之研究 Study of Molecular alteration in cancer-associated fibroblasts for induction of drug resistance of head and neck cancer |
55 |
Unstained tissue sections
|
20201117 |
| 31 |
200043 |
陳安 |
國防醫學院；病理學科 |
內源性半乳糖凝集素-3、NLRP3發炎體與自噬作用對IgA腎病變致病機制之調控 The regulation of endogenous galectin-3、NLRP3 inflammasome and autophagy in the pathogenesis of IgA nephropathy |
60 |
Serum
|
20201117 |
| 32 |
200055 |
陳相成 |
三軍總醫院；風濕免疫過敏科 |
Toll-Like Receptor 2與IL-32在系統性紅斑狼瘡中表達之關聯性與 其機轉 The relationship between TLR2 and IL-32 expression in systemic lupus erythematosus and its mechanism |
24 |
Blood DNA
|
20201207 |
| 33 |
200003 |
林凱元 |
奇美醫療財團法人奇美 醫院；醫學研究部 |
KLF16於胃癌之角色及機制探討 The role of KLF16 and its carcinogenic mechanism in gastric cancer |
35 |
Unstained tissue sections
|
20201228 |
| 34 |
200039 |
林乾閔 |
衛生福利部雙和醫院；神經外科 |
探討以Myc/PD-L1/Akt作為治療惡性腦癌標靶之轉譯研究 A translational investigation of the role of Myc/PD-L1/Akt axis as a therapeutic target for treating glioblastoma multiforme |
3 |
Unstained tissue sections
|
20201228 |
| 35 |
200047 |
劉峰誠 |
三軍總醫院；風濕免疫科 |
建立自體免疫腎炎病人之基因資料庫與個人化醫療 Establishment of genomics database of autoimmune nephritis for personalized medicine |
81 |
Serum
|
20201228 |
| 36 |
200056 |
陳相成 |
三軍總醫院；風濕免疫過敏科 |
系統性紅斑性狼瘡於CARD14、RIMS2基因表現與IFN轉錄因子表現之相關及機制性探討 The correlation and mechanism study of functional gene, CARD14 and RIMS2, with IFN transcription factor in SLE |
4 |
Serum
|
20201228 |
| 37 |
200011 |
康柏皇 |
高雄榮民總醫院；耳鼻喉頭頸部 |
透過分析mRNA微列陣資料庫研究口腔癌的代謝路徑 To identify metabolic pathway associated with oral cancer progression by analyzing mRNA database |
40 |
Tissue RNA
|
20201229 |
| 38 |
200033 |
蘇性豪 |
高雄榮民總醫院；耳鼻喉頭頸部 |
用於誘導頭頸癌細胞染色體不穩定的 PLK 抑製劑的藥物篩選 Drug Screen of PLK inhibitors for inducing chromosomal instability on head and neck cancer cells |
40 |
1.Tissue RNA
2.Unstained tissue sections
|
20201229 |
| 39 |
200042 |
高鴻偉 |
三軍總醫院；病理部 |
探討與甲狀腺癌診斷預後和抗藥性相關之生物標記 Potential bio-markers in predict prognosis and drug resistance of thyroid cancer |
1 |
Tissue RNA
|
20201229 |
| 40 |
200069 |
葉肇元 （雲象科技） |
雲象科技股份有限公司；總經理室 |
乳癌ER、PR、HER-2、Ki-67的AI model AI model of ER、PR、HER-2、Ki-67 in breast cancer |
10 |
Unstained tissue sections
|
20201231 |
| 41 |
200006 |
袁行修 |
高雄醫學大學；醫學研究所 |
提升口腔癌前病變及口腔癌診斷率之整合性研究 An integrated study for improvement of diagnostic efficiency for oral precancer and cancer |
80 |
1.Plasma
2.Buffy coat
3.Unstained tissue sections
|
20210113 |
| 42 |
200010 |
馮思中 |
長庚醫療財團法人長庚醫院；泌尿科 |
探討與鑑定上泌尿道泌尿上皮癌中好發的基因變異:在病理生理上的 應用及臨床意義 Identification and characterization of the frequent genetic alternations in upper tract urothelial carcinoma : the pathophysiological implication and clinical significance |
27 |
Unstained tissue sections
|
20210113 |
| 43 |
200016 |
林吉晉 |
林口長庚醫院；放射診療科 |
人類腸胃道腫瘤：整合影像形態學與代謝體精準醫學研究 Precision medicine for human gastric and colon cancers: Integrated metabolomics and morphomics imaging analysis |
150 |
Frozen tissue fragment
|
20210113 |
| 44 |
200017 |
周德陽 |
中國醫藥大學附設醫院；神經外科部 |
多型性膠質母細胞瘤之免疫療法預後評估與病程監測平台建構 Establishing a screening platform to evaluate the prognosis and progression for glioblastoma multiforme （GBM） treated with immunotherapeutic strategies |
33 |
Unstained tissue sections
|
20210113 |
| 45 |
200022 |
葉俊杰 |
中國醫藥大學附設醫院；一般外科部 |
探討胰臟癌多體（或組）學標記的臨床意義 Exploring the clinical significance of multi-omic markers of pancreatic cancer |
12 |
1.Tissue DNA
2.Tissue RNA
3.Unstained tissue sections
|
20210113 |
| 46 |
200067 |
王正旭 |
基隆長庚醫院；內科部血液腫瘤科 |
自我調控的STAT訊號在食道鱗狀上皮癌的預後診斷 Interaction between IL-13 and CCL5 at Esophageal Squamous Cell Carcinoma: Possible Mechanism of Tumor Progression |
10 |
Unstained tissue sections
|
20210113 |
| 47 |
200068 |
顏嘉宏 |
高雄醫學大學;天然藥物研究所 |
NRF2訊息途徑與瀰漫性大B細胞淋巴瘤治療成效之相關性分析 Association analysis of NRF2 signaling and treatment response in patients with diffuse large B cell lymphoma |
80 |
Unstained tissue sections
|
撤回 |
| 48 |
200008 |
黃昭淵 |
國立臺灣大學；醫學院泌尿科 |
發炎體基因多形性與砷暴露基因-環境交互作用對腎細胞癌化 之影響及機制探討 Effects of gene-environment interaction of inflammasome gene polymorphisms and arsenic exposure on renal cell carcinogenesis and its mechanism |
35 |
1.Tissue DNA
2.Tissue RNA
3.Plasma
4.Buffy coat
|
20210121 |
| 49 |
200044 |
陳安 |
國防醫學院；病理學科 |
以IgA1 O-聯結醣基為標靶開發IgA腎病變之診斷試劑重塑臨床評估之準則 Targeting O-glycans of IgA1 to develop diagnostic reagents for IgA nephropathy and reshape its clinical assessment protocol |
100 |
Serum
|
20210121 |
| 50 |
200002 |
黃建寧 |
中山醫學大學附設醫院；內科部 |
miR-302調控MST1及PDX-1路徑對抗糖脂毒性導致β細胞老化與凋亡之機制探討 Investigating the mechanisms of miR-302 protects against glucolipotoxicity-induced β-cell senescence and apoptosis by regulation of MST1 and PDX-1 pathway |
88 |
1.Blood DNA
2.Plasma
3.Buffy coat
|
20210122 |
| 51 |
200018 |
林精湛 |
中國醫藥大學附設醫院；血液腫瘤科 |
利用細胞內鉑金含量預測泌尿上皮癌患者接受前導性化療之療效 Using intracellular platinum content to predict outcome of urothelial carcinoma patients with neoadjuvant cisplatin treatment |
40 |
1.Tissue DNA
2.Tissue RNA
3. Frozen tissue fragment
|
20210225 |
| 52 |
200027 |
蒲永孝 |
國立臺灣大學醫學院；泌尿科 |
尋找與低度風險攝護腺癌惡化有關之基因及路徑—一個預防攝 護腺癌之新策略 Identify genes/pathways responsible for progression from low risk to higher risk prostate cancer—A new strategy for prostate cancer prevention |
60 |
Unstained tissue sections
|
20210312 |
| 53 |
200012 |
梁金銅 |
國立台灣大學醫學院附設醫院；外科部 |
比較腹腔鏡手術或機器手臂輔助手術治療經術前同步化放療之中低位直腸癌的前瞻性隨機對照試驗 A Randomized Prospective Controlled Clinical Trial Regarding the Surgical Outcomes of Robotic Approach versus Laparoscopic for the Surgery of Middle or Low Rectal Cancer After Preoperative Chemoradiation |
148 |
1.Tissue DNA
2.Plasma
|
20210316 |
| 54 |
200040 |
朱堂元 |
佛教慈濟醫院；研究部 |
三陰性乳癌與高級別漿液性卵巢癌 p53, IGF-1R, PR 表現互相擷抗 之研究 Antagonization between IGF-1R and p53 or PR in triple-negative breast cancer and ovarian high-grade serous carcinoma |
15 |
1.Unstained tissue sections
2.Tissue RNA
|
20210316 |
| 55 |
200065 |
張志隆 |
馬偕紀念醫院；醫學研究部 |
探討非 BRCA突變型卵巢癌組織中 miRNA profile與 BRCA1 表現的關聯性 Investigation of potential miRNAs profiles linking to reduced BRCA1 expression in ovarian cancer patients without genomic mutations. |
25 |
Tissue RNA
|
20210324 |
| 56 |
200015 |
孔美蘭 |
高雄榮民總醫院；教學研究部 |
探討草本芳香類奈米製劑干擾腫瘤生成及上皮細胞間質轉化對抑制尿路上皮癌的效用 To investigate the roles of herbal aromatic substances nanoparticles （HAS NPs） on inhibition of tumorigenesis and epithelial-mesenchymal transition （EMT） on human urothelial carcinoma （UC） cells |
131 |
Serum
|
20210401 |
| 57 |
200041 |
陳建隆 |
聯新國際醫院；腎臟病整合照護中心 |
探討體液中微型RNA在 泌尿道上皮癌中的功能及應用 Exploration of the functions and applications of miRNAs in urothelial carcinoma |
115 |
1.Unstained tissue sections
2.Plasma
|
20210406 |
| 58 |
200064 |
陳怡仁 |
臺北榮民總醫院；婦女醫學部 |
CD44及ALDH1在卵巢癌抗細胞凋亡所扮演的角色:著重於DNA修復的能力 The role of CD44 and ALDH1 on anti-apoptosis of ovarian cancer cells: focus on the DNA repairing capability |
2 |
Tissue RNA
|
20210406 |
| 59 |
200046 |
許仁駿 |
花蓮慈濟醫學中心；癌症研究中心 |
探討MBNL3對於卵巢癌生長及轉移的影響及分子機制（第一期） To investigate the effect of MBNL3 on the growth and metastasis of ovarian cancer and its molecular mechanism （Phase I） |
15 |
1.Unstained tissue sections
2.Tissue DNA
3. Frozen tissue fragment
|
20210701 |
| 60 |
200057 |
林子平 |
臺北榮民總醫院；泌尿部 |
探討神經內分泌分化相關長鏈非轉譯碼RNA在賀爾蒙不依賴復發型 攝護腺癌中的重要性: 找尋能成為新的癌症標誌或治療標靶之長鏈非轉譯碼RNA-第二期計畫 Study neuroendocrine differentiation-related lincRNAs in castration-resistant relapsed prostate cancer: Implication in prognosis and therapy-phase II |
85 |
Tissue RNA
|
20210719 |
| 61 |
200070 |
黃道揚 |
國家衛生研究院；癌症研究所 |
PML 在乳腺癌 發病機理作用 Role of PML in the Pathogenesis of Breast Cancer |
80 |
1.Tissue DNA
2.Tissue RNA
|
20210810 |
| 62 |
210073 |
翁菁甫 |
新竹國泰醫院；呼吸胸腔科 |
利用全基因體定序及轉錄體定序分析偵測呼吸道常見微生物菌叢與肺癌進程之相關性 Detection of airway commensal microbiome in association with lung cancer promotion by whole genome and whole-transcriptome sequencing analyses |
100 |
Unstained tissue sections
|
20210824 |
| 63 |
210072 |
黃彥鈞 |
銳準生醫股份有限公司；營運管理部門 |
使用血漿癌蛋白體進行肺癌早期篩檢之臨床應用評估計畫 Clinical Utility of Plasma Cancer Proteomic Profile for Early Detecting Lung Cancer |
105 |
Plasma
|
20210825 |
| 64 |
200009 |
朱旆億 |
秀傳醫療社團法人秀傳紀念醫院；病理科 |
三陰性乳癌細胞中LGR5蛋白參與侵襲與轉移的相關機制探討以及利 用磁性輔助配適體快速篩選平台開發抑制LGR5活性之標靶化療配適體 To investigate the malignant role of LGR5 in triple-negative breast cancer and develop LGR5 targeted chemotherapy aptamer by Magnetic-Assisted Rapid Aptamer Selection （MARAS） |
200 |
Tissue RNA
|
20211007 |
| 65 |
200066 |
楊博勝 |
馬偕紀念醫院；一般外科 |
EB病毒感染及變異基因與乳癌病人預後相關研究的驗證 Study and Validation for Epstein-Barr virus infection, genes mutation and outcome in breast cancer patients |
151 |
Tissue DNA
|
20211007 |
| 66 |
200005 |
孫定平 |
奇美醫療財團法人奇美 醫院；外科部 |
NCAPG過度表現於大腸直腸癌之臨床意義及致癌機轉 Clinical impact and carcinogenic mechanism of NCAPG overexpression in colorectal cancer |
100 |
Unstained tissue sections
|
20211217 |
| 67 |
200007 |
潘美仁 |
高雄醫學大學；臨床醫學研究所 |
表異質基因調控酵素及其抑制劑在個人化乳癌治療上的角色及應用 The role of epigenetic modifying enzymes and inhibitors in personalized therapy of breast cancer patients |
27 |
1.Tissue DNA
2.Unstained tissue sections
3.Plasma
4.Blood DNA
|
20211217 |
| 68 |
200013 |
林本仁 |
台大醫院；外科 |
探討ATMIN對於微星粒穩定大腸直腸癌的分子機轉及臨床意義 Investigation of molecular mechanism and clinical significance of ATMIN （ataxia telangiectasia mutated interactor） in colorectal cancer with MSS （microsatellite stable） status |
30 |
Unstained tissue sections
|
20211217 |
| 69 |
200019 |
黃至豪 |
中國醫藥大學附設醫院；乳房外科部 |
探討台灣年輕女性三陰性乳癌多體（或組）學標記的臨床意義 Exploring the clinical significance of multi-omic markers of young Taiwanese women with triple-negative breast cancer |
30 |
1.Tissue RNA
2.Unstained tissue sections
|
20211217 |
| 70 |
200020 |
張伸吉 |
中國醫藥大學附設醫院；大腸直腸外科部 |
探討黏液性結直腸腺癌多體（或組）學標記的臨床意義 Exploring the clinical significance of multi-omic markers of mucinous colorectal adenocarcinoma |
60 |
1.Unstained tissue sections
2.Tissue RNA
|
20211217 |
| 71 |
200034 |
趙祖怡 |
臺北醫學大學；臨床醫學研究所 |
研究BTK/HER2信號通路在HER2陽性乳腺癌生物特性角色: 調控T細胞的效應及逆轉賀癌平抗藥性的分子機制 Investigating the role of BTK/HER2 signaling as a therapeutic target for restoration of T cell function and reversal of Trastuzumab resistance in HER2+ Breast cancer |
44 |
Unstained tissue sections
|
20211217 |
| 72 |
200062 |
詹宇鈞 |
臺北榮民總醫院；病理檢驗部微生物科 |
研究巨細胞病毒US28基因型與大腸直腸癌病人預後之關連性 Study of the association among HCMV US28 genotypes and outcome of colorectal patients |
220 |
1.Tissue DNA
2.Tissue RNA
|
20211217 |
| 73 |
210071 |
曾令民 |
臺北榮民總醫院；乳房醫學中心 |
以RNA定序預測三陰性乳癌患者的治療反應並探討免疫檢查點抑制劑療法的抗藥機制 Using RNA sequencing to predict the therapeutic response and explore the resistance mechanism for immune checkpoint blockade therapy in patients with triple-negative breast cancer |
174 |
1.Tissue RNA
2.Unstained tissue sections
|
20211217 |
| 74 |
210074 |
蔡璧合 |
義守大學;醫學系 |
p73活化劑於不同構型p53突變之頭頸部鱗狀細胞癌所造成 抑制癌作用評估 Evaluation of the anti-cancer effect of p73 activator on head and neck squamous cell carcinoma with different conformation of p53 mutations |
20 |
1.Tissue RNA
2.Unstained tissue sections
|
20220107 |
| 75 |
210075 |
翁菁甫 |
新竹國泰綜合醫院;呼吸胸腔科 |
SLC7A5作為肺癌治療標靶併藥物篩選平台及臨床預後研究 SLC7A5 in lung cancer as therapeutic target and drug screen platform with analysis of clinical prognostic relevance |
100 |
Unstained tissue sections
|
20220223 |
| 76 |
220082 |
劉俊揚 |
國家衛生研究院;細胞與系統醫學研究所 |
探討Nik-related kinase調控肺腺癌腫瘤進程之角色 To investigate the role of Nik-related kinase in regulating tumor progression of lung adenocarcinoma （LAC） |
60 |
1.Frozen tissue fragment
2.Tissue RNA
3.Unstained tissue sections
|
20220223 |
| 77 |
220084 |
楊奕馨 |
國家衛生研究院；癌症研究所 |
肝癌病人接受標靶藥品治療之代謝性併發症探討 Investigate metabolic complications in liver cancer patients treated with target therapies |
6000 |
Big data
|
20220223 |
| 78 |
220077 |
羅盛典 |
長庚醫療財團法人高雄 長庚紀念醫院;耳鼻喉科 |
（NBCT）血管張力素II型受體可藉由調控Midkine表現來影響頭頸部鱗狀上皮細胞癌的預後 （NBCT） To investigate the prognosis of Midkine regulated by angiotensin receptors II in head and neck squamous cell carcinoma |
30 |
Unstained tissue sections
|
20220623 |
| 79 |
220076 |
李劭軒 |
長庚醫療財團法人高雄 長庚紀念醫院;血液腫瘤科 |
（NBCT）經由冷凍腫瘤組織、石蠟包埋腫瘤組織及血液檢體驗證醛糖還原酶家族1成員在食道鱗狀細胞癌的表現 （NBCT）Validation of the expression of aldo-keto reductase family 1 members in human esophageal squamous cell carcinoma through frozen tumor tissue, paraffin-embedded tumor tissue, and blood sample |
16 |
Serum
|
20220624 |
| 80 |
220086 |
黃奕文 |
台北醫學大學附設醫院；臨床研究中心 |
探討病毒性肝癌與脂肪性肝癌之分子特徵差異 To explore the difference in molecular signature between virus and steatosis-related liver cancer |
1050 |
1.Tissue RNA
2.Unstained tissue sections
|
20220718 |
| 81 |
220087 |
李美璇 |
國立陽明交通大學；臨床醫學研究所 |
探討基因易感受性對於膽管癌與非B非C型肝炎感染之肝細胞癌的影響 Genetic susceptibility and the associated risk of cholangiocarcinoma and non-hepatitis B and non-hepatitis C hepatocellular carcinoma |
300 |
Blood DNA
|
20220718 |
| 82 |
220078 |
曾子玲 |
偉喬生醫股份有限公司; 品保暨法規部 |
〝偉喬生醫〞硫酸吲哚酚檢測試劑組（〝Leadgene〞Indoxyl Sulfate （IS） ELISA Kit）之臨床性能研究：以國家級人體生物資料庫整合平台中慢性腎臟病患者血清檢體進行分析 Clinical Performance Study of 〝Leadgene〞Indoxyl Sulfate （IS） ELISA Kit: Using CKD Patient Serum Sample in National Biobank Consortium of Taiwan for Analysis |
200 |
Serum
|
20220812 |
| 83 |
220090 |
謝財源 |
三軍總醫院；胃腸肝膽科 |
探討CRNDE基因在肝細胞癌的調控機轉及其相關分子表現之臨床意義 To investigate the regulatory mechanisms of CRNDE gene in hepatocellular carcinoma and the clinical significance of its associated molecular expression |
50 |
Plasma
|
20220831 |
| 84 |
220091 |
王述綺 |
高雄醫學大學；醫學檢驗生物技術學系 |
探討胞外泌體內 DANCR 於預測慢性 C 型肝炎病毒治療後產生的肝癌再復發之相關性、作用機制以及作為精準醫療之可行性 Investigation of exosomal DANCR in predicting of HCC recurrence in HCV-related HCC post curative therapy, mechanism of action, and the feasibility on precision medicine application |
200 |
1.Unstained tissue array sections
2.Tissue RNA
3.Blood DNA
4.Serum
|
20220831 |
| 85 |
220093 |
許朝偉 |
林口長庚醫院；胃腸肝膽科 |
B型及D型肝炎病毒共同感染的肝癌病人中的 D型肝炎病毒突變株之分離與分析 Analyses of Hepatitis Delta Virus Mutants Isolated from Hepatocellular Carcinoma Patients Co-infected with Hepatitis B/D Viruses |
4 |
Serum
|
20220831 |
| 86 |
220079 |
黃彥鈞 |
銳準生醫股份有限公司; 營運管理部門 |
使用血漿癌蛋白體特徵進行多種癌症早期篩檢之臨床應用評估計畫 Clinical Utility of Plasma Cancer Proteomic Profile for Early Detecting Multiple Primary Cancer |
89 |
Plasma
|
20221027 |
| 87 |
220080 |
黃其晟 |
台北榮民總醫院;乳房醫學中心 |
生醫大數據導引新機制藥物開發 New drug development guided from biomedical big data |
38 |
Tissue DNA
|
20221109 |
| 88 |
220081 |
陳雅雯 |
國家衛生研究院;癌症研究所 |
利用同源小鼠口腔癌細胞株探討Cd80在口腔癌的功能角色 Functional characterization of Cd80 in oral squamous cell carcinoma using syngeneic mouse OSCC cells |
80 |
Unstained tissue sections
|
20220920 |
| 89 |
220085 |
蔡璧合 |
義守大學;醫學系 |
p73活化劑於不同構型p53突變之頭頸部鱗狀細胞癌所造成抑制癌作用評估 Evaluation of the anti-cancer effect of p73 activator on head and neck squamous cell carcinoma with different conformation of p53 mutations |
10 |
Tissue DNA
|
20221205 |
| 90 |
220083 |
王紹椿 |
中國醫藥大學附設醫院;癌症生物研究中心 |
發展新穎腫瘤及血液生物標記之有效癌症標靶治療策略 Developing novel tumor and blood biomarkers of marker guided effective cancer therapies |
298 |
Serum
|
20221213 |
| 91 |
220092 |
陳培哲 |
台大醫學院；臨床醫學研究所 |
HDV對HBV, HDV相關肝癌中HBV DNA嵌入之影響 Contribution of HDV in HBV-induced insertional mutagenesis in HBV, HDV-related HCC |
70 |
1.Tissue DNA
2.Tissue RNA
|
20221216 |
| 92 |
220094 |
葉昭廷 |
長庚大學；醫學系 |
研究載脂蛋白C1在肝癌致癌機制中所扮演的角色 Analysis of the role of ApoC1 in hepatocarcinogenesis |
200 |
1.Tissue DNA
2.Tissue RNA
|
20221216 |
|
93
|
220089
|
楊奕馨
|
國家衛生研究院癌症研究所
|
國家級人體生物資料庫整合平台癌症主題資料之資料治理計畫
Data governance for cancer-specific data in National Biobank Consortium in Taiwan
|
12000
|
Big data
|
20221219
|
|
94
|
220097
|
李東慶
|
德怡科技股份有限公司
|
肝癌相關基因甲基化研究
DNA methylation for hepatocellular carcinoma
|
25
|
Plasma
|
20230130
|
|
95
|
220095
|
謝常文
|
羅氏大藥廠;醫藥學術處
|
癌症基因醫療大數據庫之研究與應用
Re search and application of oncology clinic o gen omic big database
|
2000
|
Big data
|
20230221
|
|
96
|
220107
|
吳慧琳
|
臺大醫院；肝炎研究中心
|
B 型肝炎相關肝細胞癌早期復發研究: 著重在探討腫瘤轉移抗原1（MTA1）新穎剪接異構體，MTA1dE4，涉及的分子機制與臨床意義
Study on the early recurrence of HBV-associated hepatocellular carcinoma: with emphasis on the molecular mechanisms and clinical implications of a novel metastatic tumor antigen 1 spliced variant, MTA1dE4
|
50
|
Tissue RNA
|
20230222
|
|
97
|
230109
|
許朝偉
|
長庚醫院；胃腸肝膽科
|
B型及D型肝炎病毒共同感染的肝癌病人中的D型肝炎病毒突變株之分離與分析
Analyses of Hepatitis Delta Virus Mutants Isolated from
Hepatocellular Carcinoma Patients Co-infected withHepatitis B/D Viruses
|
70
|
Serum
|
20230222
|
|
98
|
220096
|
賴宗慶
|
臺北市立萬芳醫院；胸腔內科
|
研究鞘氨醇激酶（SPHK1 與 SPHK2）於肺腺癌中矛盾的腳色與功能
Investigate the contradictory role and function of sphingosine kinases （SPHK1 and SPHK2） in lung adenocarcinoma
|
106
|
Unstained tissue sections
|
20230306
|
|
99
|
220099
|
程毅君
|
雙和醫院；院長室
|
研究PP1R15B及其下游路徑並發展專一性標靶藥物以治療Lenvatinib頑固性耐藥之復發肝癌
Identification of Targetable mediators involving in PP1R15B Pathway to Overcome Resistance to Lenvatinib in Drug-Tolerant Persister Liver Cancer
|
40
|
Unstained tissue sections
|
20230308
|
|
100
|
220102
|
蔡若婷
|
雙和醫院；放射腫瘤科
|
pre-mRNA SRSF1與XIRP2在肝細胞癌抗輻射與轉移角色之交互作用機制探討
A Mechanism Study of the Interplay between pre-mRNA-SRSF1 and XIRP2 in Radiation Resistance and Metastasis of Hepatocellular Carcinoma
|
40
|
Unstained tissue sections
|
20230308
|
|
101
|
220088
|
徐欣伶
|
國家衛生研究院分子與基因醫學研究所
|
研究miR-34a和MCT-1對脂質代謝調控是否影響巨噬細胞分化和癌症生成
Roles of microRNA-34a and MCT-1 in lipid metabolism during macrophage reprogramming and carcinogenesis
|
60
|
1.Unstained tissue sections
2.Tissue RNA
|
20230316
|
|
102
|
220101
|
謝宜儒
|
瀚源生醫股份有限公司；品保法規部
|
以半導體生物晶片檢測血中心肌旋轉蛋白I及T之評估
A pilot study to evaluate the detection of troponin I and T from clinical specimens by semiconductor-based biosensors
|
30
|
Plasma
|
20230320
|
|
103
|
220106
|
何祥齡
|
臺北榮民總醫院；病理檢驗部 （合作廠商:創行股份有限公司）
|
感染症病原體及癌症生物標記體外檢測試劑研發及確效評估_NSCLC ALK
To validate the efficacy of microbes infectious and cancer-related biomarkers in vitro diagnostic devices_NSCLC ALK
|
20
|
Plasma
|
20230324
|
|
104
|
220104
|
林乾閔
|
雙和醫院；神經外科
|
聯合靶向Btk/PD-L1/PD-L2腫瘤免疫訊號軸作為治療抗藥性膠質母細胞瘤之治療功效及臨床前評估
Preclinical investigation of combined targeting the immune signaling axis Btk/PD-L1/PD-L2 for combating drug resistant glioblastoma multiforme
|
40
|
Unstained tissue sections
|
20230516
|
|
105
|
230108
|
許恩旗
|
國家衛生研究院；分子與基因醫學研究所
|
利用病人體液中外泌體的 miRNA 轉錄體功能性網絡分析，發展肝癌早期發現的診斷依據分子標記
Develop Liquid Biopsy-Based Exosomal Correlative Signature Utilizing Oncoprotein-microRNA-circRNA Functional Networks for Early Detection of Liver Cancer
|
200
|
Plasma
|
20230526
|
|
106
|
220098
|
鄭添祿
|
高雄醫學大學生物醫學暨環境生物學系
|
以電腦計算輔以X光晶體繞射技術及冷凍電顯精準前驅抗體基因工程全面性提升抗體藥物疾病區域選擇性並降低副作用
Precising the pro-antibody engineering by computer simulation, X-ray crystallography and cryogenic electron microscopy to comprehensively improve the disease selectivity and reduce the side effects of antibody drugs
|
215
|
Frozen tissue fragment
|
20230529
|
|
107
|
220103
|
吳佳璋
|
雙和醫院；泌尿科
|
開發前列腺癌治療成效與疾病復發的新穎預測指標：精準蛋白轉錄組學患者分層演算法
Prediction of therapy response and susceptibility to disease relapse in patients with prostate cancer: an algorithm-based proteotranscriptomics approach for patient stratification
|
40
|
Buffy coat
|
20230601
|
|
108
|
230112
|
馬念涵
|
國立中央大學；生醫科學與工程學系
|
開發與驗證血液中微型RNA做為患得CAD的預測疾病標記
Exploration and validation of microRNAs as predictive biomarkers for coronary artery disease （CAD）
|
20
|
Plasma
|
20230721
|
|
109
|
220100
|
趙祖怡
|
雙和醫院；血液腫瘤科
|
探討新型鐵凋亡生物標誌在MYC基因重排雙突變淋巴癌中的治療價值
Investigation of the diagnostic and therapeutic value to novel ferroptotic biomarkers in double hit lymphoma
|
40
|
Buffy coat
|
20230801
|
|
110
|
220105
|
林景堉
|
臺北醫學大學；醫學檢驗暨生物技術學系
|
使用凝集素-多重反應監測質譜進行檢測子宮內膜癌的臨床前試驗與臨床效能
Pre-clinical Testing and Clinical Performance for Endometrial Cancer Detection Using Lectin-Multiple Reaction Monitoring Mass Spectrometry
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118
|
Plasma
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20230801
|
|
111
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230110
|
鍾仁華
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國家衛生研究院;群體健康科學研究所
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利用多體學分析找尋三陰性乳癌的免疫相關基因及其在乳癌分化、腫瘤生成及免疫微環境之功能驗證及探討
Multi-omics analysis to identify novel immune genes for triple-negative breast cancer and functionally validating their roles in cancer subtyping, tumorigenesis and immune microenvironment
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2206
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乳癌全基因型分析及醫療數據資料庫
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審查中
|
|
112
|
230111
|
張哲維
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財團法人生物技術開發中心;藥物平台技術研究所 數位健康組
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精準醫療大數據之不同癌症生物標記開發
Development of Different Cancers Biomarkers for Precision Medicine with Big Data Analyses
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160
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1.Tissue DNA
2.Tissue RNA
3.Unstained tissue sections
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審查中
|
|
113
|
230113
|
黃綉文
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台北醫學大學附設醫院；研發部
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新穎性結構天然物萘醌衍生物於血管及淋巴管新生抑制與抗腫瘤之應用及其機轉探討
Application of novel natural naphthoquinone-based derivatives as anti-angiogenic, anti-lymphogenic and anti-tumor agents and its underlying mechanisms
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20
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Frozen tissue fragment
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審查中
|
|
114
|
230114
|
曾子玲
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偉喬生醫股份有限
公司；品保暨法規部
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〝偉喬生醫〞硫酸吲哚酚檢測試劑組（〝Leadgene〞Indoxyl Sulfate （IS） ELISA Kit）之臨床性能研究：以國家級人體生物資料庫整合平台中慢性腎臟病患者血清檢體進行分析
Clinical Performance Study of 〝Leadgene〞Indoxyl Sulfate （IS） ELISA Kit: Using CKD Patient Serum Sample in National Biobank Consortium of Taiwan for Analysis
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119
|
Serum
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審查中
|
|
115
|
230115
|
朱堂元
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花蓮慈濟醫院婦產部
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以血清FE 25細胞轉化活性作癌症偵測及腫瘤負擔估計:後續驗證及轉化活性機制分析
FE25 cell transformation as a serum bioassay to detect cancers and estimate tumor load: a validation study and characterization of the transformation activity
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440
|
Serum
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審查中
|
|
116
|
230116
|
楊宏志
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臺大醫院內科部
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完整探究肝細胞癌的腫瘤胚胎生態系統
Comprehensive Delineation of Oncofetal Ecosystem in Hepatocellular Carcinoma after Hepatectomy
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270
|
1.Tissue RNA
2.Unstained tissue sections
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20230823
|
|
117
|
230117
|
林妤軒
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錸博納生物科技股份有限公司管理部
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探討ALK+/ROS1+ NSCLC患者ALK/ROS1融合基因突變免疫組織化學染色切片結果與石蠟包埋組織RNA檢測及血漿游離RNA檢測結果一致性
Investigating the Concordance between Immunohistochemical Staining Results of ALK/ROS1 Fusion Gene Mutations and the Detection of Formalin-Fixed Paraffin-Embedded Tissue RNA or Cell-Free RNA in ALK/ROS1 Fusion-Positive NSCLC Patients
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60
|
1.Plasma
2. Tissue RNA
|
審查中
|
|
118
|
230118
|
陳東皓
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昇捷生物科技股份有限公司研發部
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開發肺癌生物標記的方法
Development of methodology for lung cancer biomarker
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140
|
Plasma
|
審查中
|
|
119
|
230119
|
葉肇元
|
雲象科技股份有限
公司總經理室
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乳癌的免疫染色及淋巴結分類計數模型
Classification model of IHC staining and lymph node in breast
cancer
|
30
|
Unstained tissue sections
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審查中
|
|
120
|
230120
|
陳怡庭
|
台中慈濟醫院病理部
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次世代定序解鎖高糖惡化大腸直腸癌預後之影響基因：由臨床結果到基礎驗證
Next-generation sequencing unlocks the genes that affect the prognosis of colorectal cancer exacerbation by high glucose: From clinical to basic research
|
200
|
Unstained Paraffin sections
|
審查中
|
|
121
|
230121
|
蘇文慧
|
長庚大學生物醫學系
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多基因風險評分執行肝癌分層篩查之可行性評估
Feasibility Assessment of Polygenic Risk Score-Stratified Screening in Hepatocellular Carcinoma
|
600
|
Blood DNA
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審查中
|
|
122
|
230122
|
蔡揚璽
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中一醫事檢驗所基因暨整合檢驗部
|
實體腫瘤泛癌基因檢測方法確認研究計畫書
Pan Cancer Molecular Biomarker in Solid Tumors Validation Plan
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318
|
1.Plasma
2.Unstained tissue sections
3. Blood DNA
|
審查中
|
|
123
|
230123
|
周雅菁
|
清華大學學士後醫學系
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研究子宮內膜異位症之致病機轉
Study the pathogenesis of endometriosis
|
49
|
1.Tissue RNA
2. Unstained Paraffin sections
3. Frozen tissue fragment
|
審查中
|
|
124
|
230124
|
陳詩政
|
國家衛生研究院癌症研究所 （合作廠商:臺灣阿斯特捷利康股份有限公司）
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運用國家級人體生物整合平台資料庫探討局部晚期或轉移性HER2陽性乳癌病患之二線治療的真實世界資料回溯性研究
National Biobank Consortium of Taiwan retrospective database research on HER2-positive advanced or metastatic breast cancer second line real-world treatment experience
|
1000
|
乳癌主題式資料庫
|
審查中
|